CBD (cannabidiol) is a compound found in cannabis that is used for several potential health benefits. It is non-psychoactive and is best supported by evidence for its effectiveness in treating some rare forms of epilepsy, such as Dravet syndrome and Lennox-Gastaut syndrome. The FDA has approved a CBD-based drug called Epidiolex for these conditions[5][7].
Beyond epilepsy, people commonly use CBD for:
- Anxiety — Research and self-reports suggest CBD may reduce anxiety and improve mood[3][4][5][7].
- Insomnia and sleep — Some studies and user experiences indicate that CBD may help improve sleep, though results are mixed and more research is needed[2][4][5][8].
- Pain (chronic, neuropathic, inflammatory) — CBD is reported to have anti-inflammatory properties and may help reduce different types of pain, including that from arthritis and diabetes complications, though findings are inconsistent especially for chronic pain[1][3][5][7][8].
- Stress relief and general well-being — Many people use CBD to relieve stress and enhance overall well-being[2][4].
- Seizure disorders — This is the most well-established medical use, especially in children with certain forms of epilepsy[5][7].
- Addiction and substance use disorders — Some early evidence suggests CBD might help reduce cravings for substances such as opioids and tobacco[5][8].
- Inflammation and oxidative stress — Animal studies suggest CBD has notable antioxidative and anti-inflammatory properties, with possible usefulness in cardiovascular, neurodegenerative, cancer, and metabolic diseases[1].
CBD can be found in a variety of products, such as oils, supplements, topical creams, drinks, and foods. While many users claim wide-ranging effects, large, high-quality clinical trials are still required for most uses. Potential users should also be aware that, despite anecdotal reports and preclinical findings, the scientific evidence is strongest only for specific seizure disorders, and mixed or limited for most other conditions[5][6][8].
References
- [1] Antioxidative and Anti-Inflammatory Properties of Cannabidiol – PMC
- [2] New Research Explores the Effects of Cannabidiol on General Health
- [3] 6 Benefits and Uses of CBD Oil (Plus Side Effects) – Healthline
- [4] Cannabidiol usage, efficacy, and side effects – Frontiers
- [5] Cannabidiol (CBD): What we know and what we don’t – Harvard Health
- [6] CBD products don’t ease pain and are potentially harmful
- [7] CBD (Cannabidiol) Health Benefits – WebMD
- [8] CBD: Does it work? Is it safe? Is it legal? – AAMC