Metformin 500 mg is primarily used to help control high blood sugar in people with type 2 diabetes mellitus. It is taken either alone or in combination with other diabetes medications, and works by improving the body’s response to insulin and reducing the amount of sugar produced by the liver[1]. The typical starting dose is 500 mg taken once or twice daily with meals, depending on the specific formulation and the patient’s needs[2]. The dosage may be adjusted by a healthcare provider based on blood sugar control, up to a maximum daily dose that varies by product[3].
In addition to its primary use in type 2 diabetes, metformin 500 mg may also be prescribed off-label (for conditions not specifically approved by regulatory agencies) for:
- Prediabetes (to help prevent or delay onset of diabetes)[5]
- Gestational diabetes (diabetes during pregnancy)[5]
- Polycystic ovary syndrome (PCOS) (to help with menstrual regulation and elevated blood sugar)[5]
- Weight gain caused by certain medications (such as antipsychotics)[5]
Metformin is considered a first-line medication for type 2 diabetes because it is effective and generally well tolerated. It should be used as part of a broader management plan, including appropriate diet and exercise[2].