Clobetasol propionate cream is a potent topical corticosteroid used to treat a variety of inflammatory skin conditions, particularly when other, less powerful steroids have not been effective[2].
It is commonly prescribed for:
- Moderate to severe plaque psoriasis[1]
- Moderate to severe eczema[2]
- Lichen sclerosus[2]
- Atopic dermatitis[3]
- Other corticosteroid-responsive dermatoses (inflammatory skin disorders)[1]
- Dermatitis[4]
Clobetasol works by reducing inflammation, redness, and itching associated with these conditions[5]. Due to its strength, it is generally used for short periods or on small areas to minimize the risk of local and systemic side effects such as skin thinning and suppression of the body’s hormone (cortisol) production[2].
It is supplied in several forms (cream, foam, gel, ointment, shampoo, solution, spray), with 0.05% being the most common strength[7]. Clobetasol should not be used on the face, groin, or underarms, or for mild dermatitis, acne, or infections unless specifically directed by a physician[2].
Always follow your doctor’s instructions on duration and amount of use. Overuse can increase the risk of side effects[5].
References
- [1] Clobetasol propionate: Uses, Interactions, Mechanism of Action
- [2] What is clobetasol propionate cream used for?
- [3] Clobetasol propionate–where, when, why?
- [4] Clobetasol for Eczema and Psoriasis
- [5] Clobetasol: Side effects, dosage, uses, and more
- [7] Clobetasol topical – Uses, Side Effects, and More