Acetaminophen is a widely used medication for relieving mild to moderate pain and reducing fever[1]. It is commonly utilized for headaches, muscle aches, menstrual cramps, colds, sore throats, toothaches, backaches, and pain associated with osteoarthritis or reactions to vaccinations[1]. In addition to these uses, acetaminophen is an ingredient in numerous over-the-counter and prescription combination products, often taken for cold and flu symptoms or in conjunction with opioid analgesics to manage moderate to severe pain[3].
This medication is often recommended for people seeking pain relief who may not be able to take nonsteroidal anti-inflammatory drugs (NSAIDs), such as those with stomach issues or kidney disease[5]. It is not habit-forming when taken as directed and is considered generally safe with proper dosing[4]. Off-label research in laboratory and preclinical studies suggests acetaminophen might also have antioxidant, cardioprotective, and neuroprotective properties, or effects on blood glucose and skeletal muscle, though additional studies are needed to confirm these potential benefits in clinical practice[2].
References
- [1] Acetaminophen: MedlinePlus Drug Information
- [2] Acetaminophen: Beyond Pain and Fever-Relieving – PMC
- [3] Acetaminophen: Uses, Interactions, Mechanism of Action – DrugBank
- [4] Acetaminophen/ibuprofen (oral route) – Side effects & dosage
- [5] Acetaminophen Explained: Uses, Dosage & Safety | TYLENOL®